Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8500737 | 0.85 | FFAR1 (0.35) | FFAR1LMNACYP1A2RAB9ASMN1; SMN2 | |
| SCHEMBL6843337 | 0.76 | FFAR1 (0.34) | FFAR1LMNACYP1A2RAB9ASMN1; SMN2 | |
| SCHEMBL27939835 | 0.66 | — | — | |
| SCHEMBL28788963 | 0.66 | — | — | |
| SCHEMBL28706738 | 0.66 | — | — | |
| SCHEMBL27661672 | 0.65 | THRB (0.30) | — | |
| SCHEMBL8499418 | 0.64 | PTGES (0.34) | FFAR1LMNACYP1A2RAB9ASMN1; SMN2 | |
| SCHEMBL8526230 | 0.64 | FFAR1 (0.32) | FFAR1LMNACYP1A2RAB9ASMN1; SMN2 | |
| SCHEMBL27587155 | 0.64 | RAB9A (0.33) | LMNACYP1A2RAB9ASMN1; SMN2 | |
| SCHEMBL8663991 | 0.63 | FFAR1 (0.34) | FFAR1LMNACYP1A2RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927156-A1 | BIPHENYL BUTYRIC ACIDS AND THEIR DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | WARNER-LAMBERT COMPANY (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998009940-A1 | BIPHENYL BUTYRIC ACIDS AND THEIR DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | WARNER-LAMBERT COMPANY (US) | 1998-03-12 | — | — | WO | disclosed |