Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768623 | 1.00 | GABRA5 (0.43) | GABRA5GABRB2HSD17B10MAPTNPC1 | |
| SCHEMBL8526643 | 0.88 | GABRA5 (0.41) | GABRA5GABRB2HSD17B10MAPTNPC1 | |
| SCHEMBL8768619 | 0.72 | GABRA5 (0.38) | GABRA5GABRB2HSD17B10MAPTNPC1 | |
| SCHEMBL9627288 | 0.71 | GABRA5 (0.43) | GABRA5GABRB2HSD17B10MAPTNPC1 | |
| SCHEMBL3999942 | 0.69 | GABRA5 (0.51) | GABRA5GABRB2HSD17B10MAPTNPC1 | |
| SCHEMBL2789164 | 0.69 | GABRA5 (0.51) | GABRA5GABRB2HSD17B10MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL8913011 | 0.68 | GABRA5 (0.50) | GABRA5GABRB2HSD17B10MAPTNPC1 | |
| SCHEMBL24769860 | 0.68 | GABRA5 (0.43) | GABRA5GABRB2HSD17B10MAPTNPC1 | |
| SCHEMBL6791297 | 0.68 | GABRA5 (0.47) | GABRA5GABRB2HSD17B10MAPTNPC1 | |
| SCHEMBL24768947 | 0.67 | MAPT (0.44) | GABRA5GABRB2HSD17B10MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620228-B1 | Novel reactive thiophosphate derivatives of thia(dia)zole acetic acid and process for preparing the same | LUCKY LTD (KR) | 1998-03-11 | — | — | EP | claimed |
| EP-0628561-B1 | Process for preparing cephalosporin compounds from reactive organic acid derivatives | LUCKY LTD (KR) | 1997-09-03 | — | — | EP | disclosed |
| US-5567813-A | Process for preparing cephalosporin compounds from reactive organic acid derivatives | LUCKY LTD. (KR) | 1996-10-22 | — | — | US | disclosed |
| EP-0628561-A1 | Process for preparing cephalosporin compounds from reactive organic acid derivatives | LUCKY LTD. (KR) | 1994-12-14 | — | — | EP | disclosed |