Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8527413 | 0.89 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9699076 | 0.85 | KMT2A (0.52) | TSHRNPC1RAB9AKMT2ALMNA | |
| SCHEMBL23326704 | 0.84 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL446340 | 0.82 | SLC6A3 (0.60) | TSHRSLC6A3NPC1RAB9AKMT2A | |
| SCHEMBL9467809 | 0.81 | CA12 (0.67) | CA12CA1CA2CA7CA9 | |
| Methoxymethane SCHEMBL28409022 | 0.80 | TSHR (0.70) | TSHRSLC6A3RAB9AKMT2ALMNA | |
| SCHEMBL8423145 | 0.80 | SLC6A3 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8528111 | 0.80 | KMT2A (0.51) | TSHRSLC6A3NPC1RAB9AKMT2A | |
| SCHEMBL27761411 | 0.80 | CA12 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8619008 | 0.79 | SLC6A3 (0.57) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433112-B1 | Modified gangliosides and the functional derivatives thereof | FIDIA SPA (IT) | 1998-10-28 | — | — | EP | disclosed |
| US-5424294-A | Treating central and peripheral nervous system disorders | FIDIA S.P.A. (IT) | 1995-06-13 | — | — | US | disclosed |
| US-5264424-A | Modified gangliosides and the functional derivatives thereof | FIDIA S.P.A. (IT) | 1993-11-23 | — | — | US | disclosed |
| CN-1051912-A | Improved gangliosides and functional derivatives thereof | FIDIA B P A (IT) | 1991-06-05 | — | — | CN | disclosed |