Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 9/20 | 0.41 |
| ▸ | NPY4R | P50391 | 2/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.39 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.36 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.36 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059809 | 0.85 | NPY1R (0.42) | NPY1RNPY4RNPY5RTPSAB1NPFFR1 | |
| SCHEMBL6899868 | 0.85 | NPY1R (0.42) | NPY1RNPY4RNPY5RTPSAB1NPFFR1 | |
| Trifluoroacetic Acid SCHEMBL649619 | 0.80 | NPY1R (0.43) | NPY1RNPY4RNPY5R | |
| Trifluoroacetic Acid SCHEMBL7045238 | 0.80 | NPY1R (0.43) | NPY1RNPY4RNPY5R | |
| SCHEMBL8111990 | 0.79 | NPY4R (0.39) | NPY1RNPY4RNPY5RTPSAB1 | |
| SCHEMBL8073040 | 0.79 | NPY1R (0.41) | NPY1RNPY4RNPY5RTPSAB1MEN1 | |
| SCHEMBL7600989 | 0.79 | NPY1R (0.41) | NPY1RNPY4RNPY5RTPSAB1NPFFR1 | |
| Hydrochloric Acid SCHEMBL8122088 | 0.79 | NPY4R (0.39) | NPY1RNPY4RNPY5RTPSAB1 | |
| SCHEMBL6898240 | 0.78 | NPY1R (0.38) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL8528714 | 0.78 | TPSAB1 (0.38) | NPY1RNPY4RNPY5RTPSAB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |