Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 2/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533251 | 0.86 | KDM4E (0.47) | XDHSLC22A12ALDH1A1LMNAKMT2A | |
| SCHEMBL8533389 | 0.84 | SLC9A1 (0.38) | ALDH1A1LMNAKMT2AKDM4ECYP1A2 | |
| SCHEMBL8534063 | 0.78 | CA1 (0.42) | ALDH1A1LMNAKMT2AHNF4AACMSD | |
| SCHEMBL29788088 | 0.76 | AKR1C2 (0.41) | XDHSLC22A12ALDH1A1KMT2AKDM4E | |
| SCHEMBL30153392 | 0.75 | HNF4A (0.56) | ALDH1A1LMNAKMT2AKDM4EHPGD | |
| SCHEMBL29226029 | 0.75 | HNF4A (0.56) | ALDH1A1LMNAKMT2AKDM4EHPGD | |
| SCHEMBL27784391 | 0.75 | ADORA1 (0.42) | XDHALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL8530215 | 0.74 | MEN1 (0.39) | ALDH1A1LMNAKMT2AKDM4ECYP1A2 | |
| SCHEMBL8533248 | 0.74 | FOLH1 (0.39) | ALDH1A1LMNAKMT2ACYP2C9SMN1; SMN2 | |
| SCHEMBL28153772 | 0.74 | HNF4A (0.54) | XDHSLC22A12ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699660-B1 | Arylbenzoylguanidines | MERCK PATENT GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5807896-A | Arylbenzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTING (DE) | 1998-09-15 | — | — | US | disclosed |
| EP-0699660-A2 | Arylbenzoylguanidines | MERCK PATENT GmbH (DE) | 1996-03-06 | — | — | EP | disclosed |