Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868503 | 0.88 | FDPS (0.52) | FDPSTBXAS1GAASMN1; SMN2FOLH1 | |
| SCHEMBL8533589 | 0.76 | FDPS (0.40) | FDPSSMN1; SMN2HTT | |
| SCHEMBL8530904 | 0.76 | CYP1A2 (0.45) | FDPSSMN1; SMN2HTT | |
| SCHEMBL8532197 | 0.76 | ANPEP (0.41) | FDPS | |
| SCHEMBL8532177 | 0.72 | FFAR1 (0.34) | SMN1; SMN2 | |
| SCHEMBL8529948 | 0.72 | FDPS (0.55) | FDPSTBXAS1KDM4E | |
| SCHEMBL8530305 | 0.72 | FDPS (0.38) | FDPSFOLH1 | |
| SCHEMBL10621413 | 0.71 | FDPS (0.71) | FDPSTBXAS1TERT | |
| SCHEMBL8531643 | 0.71 | FOLH1 (0.38) | FDPSFOLH1 | |
| SCHEMBL9116155 | 0.71 | TBXAS1 (0.46) | FDPSTBXAS1GAASMN1; SMN2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752999-B1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5698541-A | DISEASES OF CALCIUM METABOLISM; OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-16 | — | — | US | disclosed |