Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | FDPS | P14324 | 2/20 | 0.45 |
| ▸ | PTPRA | P18433 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532197 | 0.83 | ANPEP (0.41) | FDPS | |
| SCHEMBL8533589 | 0.79 | FDPS (0.40) | FDPSSMN1; SMN2RAB9AALDH1A1HTT | |
| SCHEMBL8529948 | 0.77 | FDPS (0.55) | FDPS | |
| SCHEMBL8529344 | 0.76 | FDPS (0.44) | FDPSSMN1; SMN2HTT | |
| SCHEMBL8532177 | 0.75 | FFAR1 (0.34) | SMN1; SMN2RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL8528147 | 0.75 | FDPS (0.46) | FDPSSMN1; SMN2 | |
| SCHEMBL8531643 | 0.71 | FOLH1 (0.38) | FDPS | |
| SCHEMBL10622087 | 0.71 | FDPS (0.71) | CYP1A2FDPSCYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL9116044 | 0.71 | FDPS (0.51) | CYP1A2FDPSPTPRACYP2C19SMN1; SMN2 | |
| SCHEMBL7206606 | 0.71 | CYP1A2 (0.56) | CYP1A2FDPSPTPRACYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752999-B1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5698541-A | DISEASES OF CALCIUM METABOLISM; OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-16 | — | — | US | disclosed |
| EP-0752999-A1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026358-A1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1995-10-05 | — | — | WO | disclosed |