Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.40 |
| ▸ | ALPG | P10696 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532197 | 0.89 | ANPEP (0.41) | FDPSERAP2ERAP1ANPEP | |
| SCHEMBL8745040 | 0.87 | CYP2C19 (0.34) | FDPSALPGHTTALPLALPI | |
| SCHEMBL8532177 | 0.86 | FFAR1 (0.34) | SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL8529948 | 0.85 | FDPS (0.55) | FDPSERAP2ERAP1ANPEP | |
| SCHEMBL8530904 | 0.79 | CYP1A2 (0.45) | FDPSHTTSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL8529344 | 0.76 | FDPS (0.44) | FDPSHTTSMN1; SMN2 | |
| SCHEMBL8528147 | 0.75 | FDPS (0.46) | FDPSSMN1; SMN2ERAP2ERAP1ANPEP | |
| SCHEMBL8745046 | 0.75 | FDPS (0.41) | FDPSSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL8531643 | 0.74 | FOLH1 (0.38) | FDPSLMNA | |
| SCHEMBL8532196 | 0.73 | FOLH1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752999-B1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5698541-A | DISEASES OF CALCIUM METABOLISM; OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-16 | — | — | US | disclosed |