SCHEMBL8530712

SCHEMBL8530712

CC(C)(C)OC(=O)C(CCc1ccccc1)NCC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGA4 P13612 2/20 0.52
ITGB7 P26010 2/20 0.52
CTSK P43235 2/20 0.52
CTSS P25774 2/20 0.52
NPR3 P17342 1/20 0.49
MMP1 P03956 1/20 0.47
MMP3 P08254 1/20 0.47
MMP9 P14780 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.44
REN P00797 1/20 0.43
MAPT P10636 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
POLB P06746 1/20 0.43
PRSS1 P07477 1/20 0.41
CTSG P08311 1/20 0.41
CTRB1 P17538 1/20 0.41
CMA1 P23946 1/20 0.41
TSHR P16473 1/20 0.41
AKT1 P31749 2/20 0.40
MME P08473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12221920 0.91 ITGA4 (0.51) ITGA4ITGB7CTSKCTSSNPR3
SCHEMBL10260902 0.85 SMN1; SMN2 (0.53) SMN1; SMN2MAPTTDP1TSHR
SCHEMBL14385198 0.79 MME (0.55) MMP9TSHRMME
SCHEMBL28599750 0.79 CTSK (0.53) ITGA4ITGB7CTSKCTSSNPR3
SCHEMBL7061908 0.78 CTSK (0.50) ITGA4ITGB7CTSKCTSSNPR3
Hydrochloric Acid SCHEMBL10324478 0.77 ITGA4 (0.54) ITGA4ITGB7CTSKCTSSMMP1
Hydrochloric Acid SCHEMBL10324479 0.77 ITGA4 (0.54) ITGA4ITGB7CTSKCTSSMMP1
SCHEMBL9443008 0.77 REN (0.58) ITGA4ITGB7CTSKCTSSNPR3
SCHEMBL7380184 0.77 REN (0.58) ITGA4ITGB7CTSKCTSSNPR3
SCHEMBL5732504 0.77 CTSS (0.77) CTSKCTSSAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0725084-B1 Process for preparing high molecular weight polymers BASF AG (DE) 1998-10-28 EP disclosed