Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28017155 | 0.90 | ALOX15 (0.45) | HTTHPGDIRAK4ALOX15L3MBTL1 | |
| Hydrochloric Acid SCHEMBL29712425 | 0.87 | L3MBTL1 (0.41) | HTTHPGDL3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL12677517 | 0.84 | KMT2A (0.41) | HTTHPGDIRAK4ALOX15L3MBTL1 | |
| SCHEMBL27978860 | 0.83 | KDM4E (0.37) | HTTHPGDL3MBTL1TAAR1KDM4E | |
| SCHEMBL9706821 | 0.83 | L3MBTL1 (0.38) | HTTHPGDIRAK4ALOX15L3MBTL1 | |
| SCHEMBL10589984 | 0.81 | ADRA2C (0.47) | L3MBTL1KDM4ETSHRTHRATHRB | |
| SCHEMBL10782205 | 0.80 | THRA (0.59) | KDM4ETHRATHRB | |
| SCHEMBL28024055 | 0.79 | ELANE (0.44) | HPGDALOX15L3MBTL1TAAR1KDM4E | |
| SCHEMBL2910938 | 0.79 | PTGS2 (0.52) | HPGDKDM4ETSHRALDH1A1ELANE | |
| SCHEMBL27365378 | 0.79 | KMT2A (0.42) | HTTL3MBTL1TAAR1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406429-B | Pyridazinone derivatives and their use in the treatment of cancer | 基因泰克公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-104379146-B | Inhibit the composition and method of varial polymerases | 拜奥克里斯特制药公司 | 2018-07-10 | — | — | CN | disclosed |
| CN-107406429-A | Pyridazinone derivative and its purposes in treating cancer | 基因泰克公司 | 2017-11-28 | — | — | CN | disclosed |
| CN-106573073-A | FAP-activated therapeutics and uses related thereto | 塔夫茨大学信托人 | 2017-04-19 | — | — | CN | disclosed |
| CN-104379146-A | Compositions and methods for inhibiting viral polymerase | BIOCRYST PHARM INC | 2015-02-25 | — | — | CN | disclosed |
| US-5807875-A | OBESITY THERAPY | DR. KARL THOMAE GMBH (DE) | 1998-09-15 | — | — | US | disclosed |