SCHEMBL8533012

SCHEMBL8533012

CCCC(N)(CCCN)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ODC1 P11926 2/20 0.62
ARG2 P78540 11/20 0.46
ARG1 P05089 10/20 0.46
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP1A2 P05177 1/20 0.44
THRB P10828 1/20 0.44
KMT2A Q03164 1/20 0.44
FDPS P14324 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11267850 1.00 ODC1 (0.62) ODC1ARG2ARG1KDM4ELMNA
SCHEMBL11267854 1.00 ODC1 (0.62) ODC1ARG2ARG1KDM4ELMNA
SCHEMBL27406408 0.88 ODC1 (0.58) ODC1ARG2ARG1MEN1ALDH1A1
SCHEMBL23010905 0.87 ARG1 (0.48) ODC1ARG2ARG1MEN1ALDH1A1
SCHEMBL348479 0.87 MEN1 (0.54) ODC1ARG2ARG1LMNAMEN1
SCHEMBL20156725 0.85 ARG2 (0.52) ODC1ARG2ARG1MEN1ALDH1A1
SCHEMBL4884641 0.85 ODC1 (0.64) ODC1ARG2ARG1KDM4ELMNA
SCHEMBL4884638 0.85 ODC1 (0.64) ODC1ARG2ARG1KDM4ELMNA
SCHEMBL4884643 0.85 ODC1 (0.64) ODC1ARG2ARG1KDM4ELMNA
SCHEMBL264841 0.84 ODC1 (0.53) ODC1ARG2ARG1MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0618192-B1 Homobidental, trifunctional maleimide linkers and their application in immunologically active conjugates BOEHRINGER MANNHEIM GMBH (DE) 1998-09-16 EP disclosed
US-5601824-A Homobidental, trifunctional linkers used in immunologically active conjugates BOEHRINGER MANNHEIM GMBH (DE) 1997-02-11 US disclosed
US-5519142-A Homobidental, trifunctional linkers, method for their preparation and use in immunologically active conjugates BOEHRINGER MANNHEIM GMBH (DE) 1996-05-21 US disclosed
EP-0618192-A1 Homobidental, trifunctional mazeimide linkers and their application in immunologically active conjugates Roche Diagnostics GmbH (DE) 1994-10-05 EP disclosed
US-4339589-A Preparation of 4-substituted oxazolidin-5-ones BASF AKTIENGESELLSCHAFT (DE) 1982-07-13 US disclosed
US-4264771-A Alkylation of substituted oxazolinone-(5) compounds BASF AKTIENGESELLSCHAFT (DE) 1981-04-28 US disclosed