Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.55 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL8535164 | 0.89 | AGBL2 (0.57) | ATMKDM4EL3MBTL1PLA2G1BNPSR1 | |
| Fumaric Acid SCHEMBL8535167 | 0.89 | AGBL2 (0.57) | ATMKDM4EL3MBTL1PLA2G1BNPSR1 | |
| SCHEMBL8531089 | 0.88 | SLC6A4 (0.59) | ATMKDM4EL3MBTL1PLA2G1BNPSR1 | |
| SCHEMBL4731272 | 0.78 | AGBL2 (0.81) | KDM4EAGBL2 | |
| SCHEMBL8534966 | 0.78 | SLC6A4 (0.56) | ATMKDM4EL3MBTL1PLA2G1BNPSR1 | |
| SCHEMBL8530523 | 0.77 | SLC6A4 (0.56) | ATMKDM4EL3MBTL1AGBL2SLC6A4 | |
| SCHEMBL8532008 | 0.74 | SLC6A4 (0.65) | ATMKDM4EL3MBTL1AGBL2SLC6A4 | |
| SCHEMBL8533467 | 0.73 | AGBL2 (0.55) | KDM4EAGBL2 | |
| Hydrochloric Acid SCHEMBL8530200 | 0.72 | SLC6A4 (0.63) | ATMKDM4EL3MBTL1PLA2G1BNPSR1 | |
| SCHEMBL14924104 | 0.71 | CYP1A2 (0.41) | KDM4EL3MBTL1SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859757-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | Farmak A.S. (CZ) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997017325-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | FARMAK A.S. (CZ) | 1997-05-15 | — | — | WO | disclosed |