Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529827 | 0.89 | ALDH1A1 (0.42) | AGBL2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL4732967 | 0.85 | AGBL2 (0.62) | AGBL2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL8530038 | 0.84 | AGBL2 (0.57) | AGBL2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL8529753 | 0.80 | SLC6A9 (0.47) | ALDH1A1KMT2AHPGDMEN1MAPT | |
| SCHEMBL8530695 | 0.77 | HPGD (0.48) | AGBL2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL8529725 | 0.74 | HPGD (0.45) | AGBL2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL4731272 | 0.74 | AGBL2 (0.81) | AGBL2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL8533439 | 0.73 | ATM (0.55) | AGBL2KDM4E | |
| SCHEMBL10383444 | 0.73 | AGBL2 (0.50) | AGBL2ALDH1A1KMT2AMEN1NPC1 | |
| Fumaric Acid SCHEMBL8535167 | 0.72 | AGBL2 (0.57) | AGBL2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859757-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | Farmak A.S. (CZ) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997017325-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | FARMAK A.S. (CZ) | 1997-05-15 | — | — | WO | disclosed |