SCHEMBL890520

SCHEMBL890520

O=C(Cl)c1ccc(C(=O)Cl)c(S(=O)(=O)O)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 1/20 0.34
ALDH1A1 P00352 6/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
KMT2A Q03164 2/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 2/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KIF11 P52732 1/20 0.31
ADCY10 Q96PN6 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALOX12 P18054 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7932106 0.98 CDC25B (0.33) CDC25BALDH1A1TSHRHSD17B10TDP1
SCHEMBL8533484 0.86 KDM4E (0.33) CDC25BALDH1A1TSHRHSD17B10CASP1
SCHEMBL20590494 0.85 CDC25B (0.34) CDC25BALDH1A1TSHRTDP1KMT2A
SCHEMBL28023399 0.84 CDC25B (0.36) CDC25BALDH1A1TSHRHSD17B10TDP1
SCHEMBL7932105 0.81 ALDH1A1 (0.35) CDC25BALDH1A1TSHRHSD17B10TDP1
SCHEMBL8533482 0.78 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10TDP1KMT2A
SCHEMBL9828047 0.76 ALDH1A1 (0.32) ALDH1A1HSD17B10TDP1CASP1CASP7
SCHEMBL101687 0.75 TSHR (0.45) ALDH1A1TSHRCASP1KMT2AMAPT
SCHEMBL28119174 0.75 NPC1 (0.46) ALDH1A1KMT2ALMNAMAPTALOX15
SCHEMBL27821936 0.75 CES2 (0.46) ALDH1A1TSHRHSD17B10KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE45850-E1 Composition of organic compounds, optical film and method of production thereof CRYSOPTIX K.K. (JP) 2016-01-19 US disclosed
EP-2638126-B1 NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER CRYSOPTIX KK (JP) 2015-02-18 EP disclosed
US-8895118-B2 Negative dispersion retardation plate and achromatic circular polarizer CRYSOPTIX K.K. (JP) 2014-11-25 US disclosed
US-20140334002-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2014-11-13 US disclosed
EP-2638126-A1 NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER CRYSOPTIX K.K. (JP) 2013-09-18 EP disclosed
EP-2630523-A1 RETARDER AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME CRYSOPTIX K.K. (JP) 2013-08-28 EP disclosed
US-8512824-B2 Composition of organic compounds, optical film and method of production thereof CRYSOPTIX KK (JP) 2013-08-20 US disclosed
EP-2622392-A1 PATTERNED RETARDER CRYSOPTIX K.K. (JP) 2013-08-07 EP disclosed
EP-2331655-B1 COMPOSITION OF ORGANIC COMPOUNDS, OPTICAL FILM AND METHOD OF PRODUCTION THEREOF CRYSOPTIX KK (JP) 2013-07-03 EP disclosed
US-20130003178-A1 THREE-DIMENSIONAL CIRCULAR POLARIZATION EYEGLASSES CRYSOPTIX KK (JP) 2013-01-03 US disclosed
WO-2013003780-A1 THREE-DIMENSIONAL CIRCULAR POLARIZATION EYEGLASSES CRYSOPTIX KK (JP) 2013-01-03 WO disclosed
WO-2012064618-A1 NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER CRYSOPTIX KK (JP) 2012-05-18 WO disclosed
US-20120113380-A1 NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER CRYSOPTIX KK (JP) 2012-05-10 US disclosed
US-20120099052-A1 RETARDER AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME CRYSOPTIX KK (JP) 2012-04-26 US disclosed
WO-2012052950-A1 RETARDER AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME CRYSOPTIX KK (JP) 2012-04-26 WO disclosed
WO-2012044867-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2012-04-05 WO disclosed
US-20120081784-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2012-04-05 US disclosed
EP-2331655-A2 COMPOSITION OF ORGANIC COMPOUNDS, OPTICAL FILM AND METHOD OF PRODUCTION THEREOF CRYSOPTIX K.K. (JP) 2011-06-15 EP disclosed
US-20100085521-A1 Composition of Organic Compounds, Optical Film and Method of Production Thereof CRYSOPTIX KK (JP) 2010-04-08 US disclosed
WO-2010020928-A2 COMPOSITION OF ORGANIC COMPOUNDS, OPTICAL FILM AND METHOD OF PRODUCTION THEREOF CRYSOPTIX KK (JP) 2010-02-25 WO disclosed