SCHEMBL8533484

SCHEMBL8533484

O=C(Cl)c1ccc(C(=O)OC(=O)c2ccc(C(=O)Cl)cc2S(=O)(=O)O)c(S(=O)(=O)O)c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HSD17B10 Q99714 2/20 0.33
ALDH1A1 P00352 7/20 0.32
MAPT P10636 3/20 0.32
TSHR P16473 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
LMNA P02545 1/20 0.32
KMT2A Q03164 1/20 0.32
HPGD P15428 2/20 0.31
CDC25B P30305 1/20 0.31
STAT3 P40763 1/20 0.31
NPSR1 Q6W5P4 2/20 0.31
PKM P14618 1/20 0.30
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8533482 0.91 ALDH1A1 (0.39) KDM4ESMN1; SMN2HSD17B10ALDH1A1MAPT
SCHEMBL890520 0.86 CDC25B (0.34) KDM4ESMN1; SMN2HSD17B10ALDH1A1MAPT
SCHEMBL8407442 0.85 CDC25B (0.46) KDM4ESMN1; SMN2MAPTTSHRL3MBTL1
SCHEMBL7932106 0.84 CDC25B (0.33) SMN1; SMN2HSD17B10ALDH1A1MAPTTSHR
SCHEMBL8407447 0.78 KDM4E (0.44) KDM4EALDH1A1MAPTTSHRLMNA
SCHEMBL28023399 0.78 CDC25B (0.36) KDM4ESMN1; SMN2HSD17B10ALDH1A1TSHR
SCHEMBL28994764 0.78 ALDH1A1 (0.38) KDM4ESMN1; SMN2HSD17B10ALDH1A1MAPT
SCHEMBL11545969 0.76 LMNA (0.38) KDM4ESMN1; SMN2HSD17B10ALDH1A1MAPT
SCHEMBL576237 0.76 CES2 (0.41) KDM4ESMN1; SMN2L3MBTL1LMNAGAA
SCHEMBL26351349 0.76 KDM4E (0.37) KDM4ESMN1; SMN2HSD17B10ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0517203-B1 Acid-dye resistant polyamide products and process for preparation BASF CORP (US) 1998-02-04 EP claimed
US-5562871-A CHEMICALLY BLOCKING A PORTION OF AMINO END GROUPS IN SULPHONATED POLYMER BASF CORPORATION (US) 1996-10-08 US claimed
US-5560973-A SULFONATED POLYMER BASF CORPORATION (US) 1996-10-01 US claimed
US-5548037-A INCLUDING SULFONATED GROUPS AND AN AMINE END BLOCKER BASF CORPORATION (US) 1996-08-20 US claimed
US-5545363-A SULFONATING, PIGMENTING, BLOCKING SULFONATED POLYAMIDE, FINALLY MELT SPINNING BASF CORPORATION (US) 1996-08-13 US claimed
US-5340886-A Acylation with a sulfonate compound, coloring, blocking and amidation with an alkyl anhydride, alkylaryl anhydride or a lactones BASF CORPORATION (US) 1994-08-23 US claimed
EP-0517203-A2 Acid-dye resistant polyamide products and process for preparation BASF CORPORATION (US) 1992-12-09 EP claimed
EP-0517203-B1 Acid-dye resistant polyamide products and process for preparation BASF CORP (US) 1998-02-04 EP disclosed
US-5562871-A CHEMICALLY BLOCKING A PORTION OF AMINO END GROUPS IN SULPHONATED POLYMER BASF CORPORATION (US) 1996-10-08 US disclosed
US-5560973-A SULFONATED POLYMER BASF CORPORATION (US) 1996-10-01 US disclosed
US-5548037-A INCLUDING SULFONATED GROUPS AND AN AMINE END BLOCKER BASF CORPORATION (US) 1996-08-20 US disclosed
US-5545363-A SULFONATING, PIGMENTING, BLOCKING SULFONATED POLYAMIDE, FINALLY MELT SPINNING BASF CORPORATION (US) 1996-08-13 US disclosed
US-5340886-A Acylation with a sulfonate compound, coloring, blocking and amidation with an alkyl anhydride, alkylaryl anhydride or a lactones BASF CORPORATION (US) 1994-08-23 US disclosed
EP-0517203-A2 Acid-dye resistant polyamide products and process for preparation BASF CORPORATION (US) 1992-12-09 EP disclosed
US-3996202-A Process for the preparation of sulfonate group containing aromatic polyamides HOECHST AKTIENGESELLSCHAFT (DT) 1976-12-07 US disclosed
US-3996202-A Process for the preparation of sulfonate group containing aromatic polyamides HOECHST AKTIENGESELLSCHAFT (DT) 1976-12-07 US disclosed