Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | CIT | O14578 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 4/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.30 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 3/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1314596 | 0.83 | ADRB2 (0.72) | ADRB2PDE2ATDP1ROCK2ROCK1 | |
| SCHEMBL3769642 | 0.78 | TYR (0.44) | ADRB2TDP1CYP3A4ESR1ESR2 | |
| SCHEMBL17540834 | 0.75 | ADRB2 (0.70) | ADRB2PDE2AKDM4EMAPTLMNA | |
| SCHEMBL2187080 | 0.75 | ADRB2 (0.70) | ADRB2PDE2AKDM4EMAPTLMNA | |
| SCHEMBL17540836 | 0.75 | ADRB2 (0.70) | ADRB2PDE2AKDM4EMAPTLMNA | |
| SCHEMBL8535317 | 0.73 | SLC6A4 (0.55) | TDP1CYP3A4ESR1KDM4EMAPT | |
| SCHEMBL334558 | 0.72 | ADRB2 (0.59) | ADRB2PDE2ATDP1LMNA | |
| SCHEMBL353336 | 0.72 | ADRB2 (0.59) | ADRB2PDE2ATDP1LMNA | |
| SCHEMBL342044 | 0.72 | ADRB2 (0.59) | ADRB2PDE2ATDP1CYP3A4ROCK2 | |
| Hydrochloric Acid SCHEMBL28673897 | 0.72 | ADRB2 (0.67) | ADRB2PDE2AROCK2ROCK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789551-A4 | HAIR CARE PERMING AGENTS AND PROCESSES | LAU JOHN R (US) | 1998-12-02 | — | — | EP | claimed |
| EP-0789551-A1 | HAIR CARE PERMING AGENTS AND PROCESSES | LAU, John R. (US) | 1997-08-20 | — | — | EP | claimed |
| WO-1997011672-A1 | HAIR CARE PERMING AGENTS AND PROCESSES | LAU JOHN R (US) | 1997-04-03 | — | — | WO | claimed |