Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 16/20 | 0.40 |
| ▸ | CA2 | P00918 | 16/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 9/20 | 0.39 |
| ▸ | CA9 | Q16790 | 9/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532987 | 0.85 | ITGB3 (0.38) | CA1CA2LMNASMN1; SMN2CA12 | |
| SCHEMBL8534198 | 0.78 | LMNA (0.40) | CA1CA2LMNASMN1; SMN2CA12 | |
| SCHEMBL8534686 | 0.77 | FEN1 (0.44) | CA1CA2LMNASMN1; SMN2CA12 | |
| SCHEMBL8428884 | 0.76 | ITGB3 (0.42) | CA1CA2LMNASMN1; SMN2CA12 | |
| SCHEMBL7863259 | 0.76 | PKM (0.46) | CA1CA2LMNASMN1; SMN2CA12 | |
| SCHEMBL8532235 | 0.75 | CA1 (0.40) | CA1CA2LMNASMN1; SMN2CA12 | |
| SCHEMBL30360302 | 0.71 | MAPT (0.46) | CA1CA2LMNASMN1; SMN2CA12 | |
| SCHEMBL27518770 | 0.69 | KDM4E (0.43) | CA1CA2LMNACA12CA9 | |
| SCHEMBL13715863 | 0.69 | PKM (0.46) | CA1CA2LMNASMN1; SMN2HPGD | |
| SCHEMBL8496886 | 0.68 | ITGB3 (0.45) | CA1CA2CA12CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |