Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 9/20 | 0.39 |
| ▸ | CA2 | P00918 | 9/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGAV | P06756 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532235 | 0.92 | CA1 (0.40) | FEN1CA1CA2CA12CA9 | |
| SCHEMBL8532987 | 0.92 | ITGB3 (0.38) | FEN1CA1CA2CA12CA9 | |
| SCHEMBL8534198 | 0.81 | LMNA (0.40) | FEN1CA1CA2CA12CA9 | |
| SCHEMBL8534236 | 0.77 | CA1 (0.40) | FEN1CA1CA2CA12CA9 | |
| SCHEMBL7856530 | 0.76 | CA1 (0.54) | CA1CA2MAPTITGB3ITGAV | |
| SCHEMBL8532217 | 0.71 | KDM4E (0.45) | CA1CA2CA12CA9LMNA | |
| SCHEMBL2836646 | 0.69 | MEN1 (0.47) | CA1CA2CA9LMNASMN1; SMN2 | |
| SCHEMBL2842084 | 0.69 | KMT2A (0.45) | CA1CA2CA12CA9LMNA | |
| SCHEMBL8534762 | 0.69 | MMP1 (0.39) | CA1CA2CA12CA9LMNA | |
| SCHEMBL30360302 | 0.69 | MAPT (0.46) | CA1CA2CA12CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |