Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 3/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8429105 | 0.86 | PLAU (0.38) | HTTMAPTRAB9AMEN1KMT2A | |
| SCHEMBL8429236 | 0.75 | PLAU (0.36) | HTTMAPTRAB9AMEN1KMT2A | |
| SCHEMBL8432291 | 0.73 | RXFP1 (0.40) | HTTMAPTRAB9AKMT2ARXFP1 | |
| Bicarbonate SCHEMBL7469511 | 0.71 | MAPT (0.65) | HTTMAPTRAB9AMEN1KMT2A | |
| SCHEMBL8432256 | 0.70 | L3MBTL1 (0.38) | HTTMAPTRAB9AMEN1KMT2A | |
| SCHEMBL4714552 | 0.69 | PLAU (0.60) | HTTMAPTRAB9AMEN1KMT2A | |
| Bicarbonate SCHEMBL8492631 | 0.68 | NPC1 (0.61) | RAB9AMEN1KMT2APLAURXFP1 | |
| Bicarbonate SCHEMBL27820322 | 0.68 | NPC1 (0.61) | RAB9AMEN1KMT2APLAURXFP1 | |
| SCHEMBL16450915 | 0.67 | HDAC8 (0.53) | HTTMAPTMEN1KMT2ARXFP1 | |
| SCHEMBL1999954 | 0.67 | ALDH1A1 (0.61) | HTTMAPTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |