Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | F13A1 | P00488 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8429249 | 0.81 | MAPK1 (0.33) | KMT2ABCHEACHEMAPK1 | |
| SCHEMBL8429109 | 0.78 | MEN1 (0.37) | KMT2AMEN1MAPK1CA1CA2 | |
| SCHEMBL8432262 | 0.71 | ERCC5 (0.38) | KMT2AMEN1MAPK1CA1CA2 | |
| SCHEMBL8432297 | 0.70 | RAB9A (0.43) | KMT2AMEN1MAPK1NPC1RAB9A | |
| SCHEMBL8542420 | 0.70 | MAPK1 (0.37) | KMT2AMEN1PLAUMAPK1NPC1 | |
| SCHEMBL8534298 | 0.69 | KMT2A (0.34) | KMT2AMEN1TGM2MAPK1NPC1 | |
| SCHEMBL6777725 | 0.66 | RAB9A (0.50) | KMT2AMEN1CA1CA2NPC1 | |
| SCHEMBL7863184 | 0.66 | MAPK1 (0.56) | KMT2AMEN1MAPK1CA12CA1 | |
| SCHEMBL19443946 | 0.64 | ALDH1A1 (0.48) | KMT2AMAPK1CA1CA2NPC1 | |
| SCHEMBL5251358 | 0.63 | PARP10 (0.44) | KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |