Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | FABP1 | P07148 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534258 | 0.81 | KMT2A (0.34) | MAPK1KMT2ABCHEACHE | |
| SCHEMBL8432262 | 0.75 | ERCC5 (0.38) | MAPK1KMT2AMITFPOLBHTT | |
| SCHEMBL8429109 | 0.71 | MEN1 (0.37) | MAPK1KMT2AMITFPOLBFABP1 | |
| SCHEMBL8542420 | 0.67 | MAPK1 (0.37) | MAPK1KMT2AALDH1A1POLBHTT | |
| SCHEMBL8534298 | 0.67 | KMT2A (0.34) | MAPK1KMT2APOLBHTT | |
| SCHEMBL7863184 | 0.66 | MAPK1 (0.56) | MAPK1KMT2AMITFALDH1A1HTT | |
| SCHEMBL6777725 | 0.64 | RAB9A (0.50) | KMT2AMITFALDH1A1POLB | |
| SCHEMBL8432297 | 0.63 | RAB9A (0.43) | MAPK1KMT2AALDH1A1POLB | |
| SCHEMBL19443946 | 0.62 | ALDH1A1 (0.48) | MAPK1KMT2AALDH1A1HTT | |
| SCHEMBL7787102 | 0.62 | KMT2A (0.47) | KMT2AALDH1A1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952381-A | SELECTIVELY INHIBITING OR ANTAGONIZING THE INTEGRINS; ANTITUMOR AGENTS, ANTIARTHRITIC AGENTS, VIRICIDES, MICROBIOCIDES; TREATING OSTEOPOROSIS, SKIN DISORDERS | G. D. SEARLE & CO. (US) | 1999-09-14 | — | — | US | disclosed |