Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | TGM2 | P21980 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8429109 | 0.72 | MEN1 (0.37) | KMT2AMEN1RAB9AMAPTMAPK1 | |
| SCHEMBL8432262 | 0.70 | ERCC5 (0.38) | KMT2AMEN1RAB9AMAPTHTT | |
| SCHEMBL8534258 | 0.69 | KMT2A (0.34) | KMT2AMEN1TGM2RAB9AMAPK1 | |
| SCHEMBL8429249 | 0.67 | MAPK1 (0.33) | KMT2AHTTMAPK1POLB | |
| SCHEMBL8432441 | 0.66 | KMT2A (0.32) | KMT2AMEN1RAB9ASTSNPC1 | |
| SCHEMBL8429467 | 0.66 | CYP1A2 (0.41) | KMT2AMEN1RAB9AMAPTMAPK1 | |
| SCHEMBL8538198 | 0.65 | CA1 (0.38) | KMT2AMEN1TGM2RAB9AMAPT | |
| SCHEMBL8532972 | 0.65 | KMT2A (0.33) | KMT2AMEN1RAB9AMAPTNPC1 | |
| SCHEMBL6777725 | 0.65 | RAB9A (0.50) | KMT2AMEN1RAB9AMAPTNPC1 | |
| SCHEMBL8542579 | 0.65 | CA1 (0.39) | KMT2AMEN1TGM2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |