Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538683 | 0.77 | KMT2A (0.39) | CYP19A1PTGS2KMT2AHPGDMAPK1 | |
| SCHEMBL8534397 | 0.76 | PPARG (0.34) | PTGS2PTPN1ALDH1A1KDM4E | |
| SCHEMBL6964782 | 0.73 | PPARD (0.40) | HPGDPTPN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8538469 | 0.67 | ALOX5 (0.38) | PTGS2KMT2AHPGDMAPK1PTPN1 | |
| SCHEMBL7378712 | 0.65 | ABCG2 (0.46) | CYP19A1KMT2AHPGDMAPK1MAPT | |
| SCHEMBL538524 | 0.64 | CYP19A1 (0.76) | CYP19A1KMT2AHPGDMAPK1ALDH1A1 | |
| SCHEMBL8538467 | 0.64 | PPARG (0.37) | PTGS2KMT2AHPGDPTPN1ALDH1A1 | |
| SCHEMBL8365863 | 0.62 | CYP19A1 (0.73) | CYP19A1KMT2AHPGDMAPK1ALDH1A1 | |
| SCHEMBL4205339 | 0.62 | CYP19A1 (0.73) | CYP19A1KMT2AHPGDMAPK1ALDH1A1 | |
| SCHEMBL28795788 | 0.62 | CYP19A1 (0.73) | CYP19A1KMT2AHPGDMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |