Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.37 |
| ▸ | PPARA | Q07869 | 10/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.36 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.36 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535732 | 0.88 | KDM4E (0.39) | PTGS2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL8535968 | 0.83 | NPC1 (0.37) | PPARGPPARAPTGS2KDM6BKDM4A | |
| SCHEMBL8336040 | 0.82 | KDM6B (0.30) | PTGS2KDM6BKDM4AKDM4DKDM3B | |
| SCHEMBL8538590 | 0.81 | ALDH1A1 (0.38) | PPARGPPARAKDM4EALDH1A1GAA | |
| SCHEMBL8534397 | 0.78 | PPARG (0.34) | PPARGPPARAPTGS2KDM4EALDH1A1 | |
| SCHEMBL8538683 | 0.75 | KMT2A (0.39) | PTGS2KDM4EGPR84PTPN1HPGD | |
| SCHEMBL8539942 | 0.75 | MEN1 (0.34) | PPARGPPARAKDM4EALDH1A1GAA | |
| SCHEMBL7375775 | 0.74 | HTR2B (0.50) | PPARGPTGS2GPR84CA12CA1 | |
| SCHEMBL11787842 | 0.74 | ALDH1A1 (0.45) | PTGS2KDM4EALDH1A1GPR84GAA | |
| SCHEMBL6957097 | 0.74 | CYSLTR1 (0.41) | GPR84PTPN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |