Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538683 | 0.78 | KMT2A (0.39) | PTGS2KDM4ELMNANPC1GPR84 | |
| SCHEMBL6956259 | 0.77 | XDH (0.48) | KDM5APOLBSMN1; SMN2PLA2G4AALOX15 | |
| SCHEMBL8434646 | 0.77 | KDM4E (0.54) | KDM5AKDM4EPOLBHPGDMAPK1 | |
| SCHEMBL6959585 | 0.76 | FABP4 (0.45) | KDM5APLA2G2AKDM4ELMNAPOLB | |
| SCHEMBL8538467 | 0.73 | PPARG (0.37) | PTGS2KDM4EGPR84HPGDKMT2A | |
| SCHEMBL6952547 | 0.72 | ABCB1 (0.50) | PTGS2LMNAPTPN1 | |
| SCHEMBL6956331 | 0.72 | SLC16A3 (0.46) | NPC1RAB9AKMT2A | |
| SCHEMBL7375775 | 0.72 | HTR2B (0.50) | PTGS2GPR84 | |
| SCHEMBL11787842 | 0.72 | ALDH1A1 (0.45) | PTGS2KDM4ERAB9ASMN1; SMN2GPR84 | |
| SCHEMBL6957097 | 0.72 | CYSLTR1 (0.41) | POLBSMN1; SMN2GPR84PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |