Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.34 |
| ▸ | PPARA | Q07869 | 12/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.33 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538467 | 0.78 | PPARG (0.37) | PPARGPPARAPTGS2KDM6BKDM4A | |
| SCHEMBL8534402 | 0.76 | CYP19A1 (0.36) | PTGS2PTPN1KDM4EALDH1A1 | |
| SCHEMBL6964782 | 0.72 | PPARD (0.40) | PPARGPPARAPTPN1KDM4EALDH1A1 | |
| SCHEMBL8535968 | 0.67 | NPC1 (0.37) | PPARGPPARAPTGS2KDM6BKDM4A | |
| SCHEMBL7378712 | 0.64 | ABCG2 (0.46) | KDM4EALDH1A1 | |
| SCHEMBL8538683 | 0.63 | KMT2A (0.39) | PTGS2PTPN1KDM4E | |
| SCHEMBL8538469 | 0.62 | ALOX5 (0.38) | PTGS2KDM6BKDM4AKDM4DKDM3B | |
| SCHEMBL8538590 | 0.62 | ALDH1A1 (0.38) | PPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL6955483 | 0.61 | ABCB1 (0.48) | — | |
| SCHEMBL7375775 | 0.61 | HTR2B (0.50) | PPARGPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |