Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 3/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536081 | 0.73 | GABRA1 (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7373615 | 0.71 | GPR132 (0.39) | CHRM2CHRM1CHRM3GPR132BRD4 | |
| SCHEMBL7457663 | 0.70 | GPR132 (0.40) | CHRM2CHRM1CHRM3GPR132BRD4 | |
| SCHEMBL8534849 | 0.70 | GPR132 (0.38) | CHRM2CHRM1CHRM3GPR132LMNA | |
| SCHEMBL9037973 | 0.65 | LMNA (0.39) | CHRM2CHRM1CHRM3GPR132BRD4 | |
| SCHEMBL9037970 | 0.63 | P2RY12 (0.36) | GPR132BRD4CREBBPPRKDCP2RY12 | |
| SCHEMBL9037967 | 0.61 | HCAR2 (0.39) | CHRM2CHRM1CHRM3GPR132BRD4 | |
| SCHEMBL7371301 | 0.60 | PRKDC (0.38) | BRD4CREBBPPRKDCPIK3CD | |
| SCHEMBL7457650 | 0.60 | GPR132 (0.40) | GPR132BRD4CREBBP | |
| SCHEMBL14415502 | 0.60 | CHRNB2 (0.41) | CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |