Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533129 | 0.83 | DRD2 (0.45) | DRD2HTR2A | |
| SCHEMBL6936021 | 0.67 | UGT2B17 (0.44) | DRD2 | |
| SCHEMBL8536476 | 0.64 | NQO2 (0.47) | DRD2HTR2A | |
| SCHEMBL7701890 | 0.62 | SLC22A12 (0.33) | — | |
| SCHEMBL8531766 | 0.61 | HTR1A (0.33) | DRD2HTR2A | |
| SCHEMBL12354607 | 0.61 | UGT2B17 (0.55) | — | |
| SCHEMBL12354606 | 0.60 | DRD2 (0.31) | DRD2 | |
| SCHEMBL15161703 | 0.60 | MAOA (0.66) | DRD2 | |
| SCHEMBL11737539 | 0.59 | NQO2 (0.45) | HTR2A | |
| SCHEMBL23828684 | 0.59 | HRH3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847159-A | 1- ω-(3,4-dihydro-2-naphthalenyl)alkyl!-cyclic amine derivatives, process for preparing the same, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-12-08 | — | — | US | disclosed |
| EP-0825180-A1 | 1-OMEGA-(3,4-DIHYDRO-2-NAPHTHALENYL)ALKYL] CYCLIC AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |