Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.37 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534971 | 0.78 | TXNRD1 (0.39) | SMN1; SMN2NPC1RAB9AHPGDTXNRD1 | |
| SCHEMBL8537928 | 0.73 | GPR88 (0.47) | SMN1; SMN2NPC1RAB9AHPGDTXNRD1 | |
| SCHEMBL1507761 | 0.68 | HPGD (0.49) | SMN1; SMN2NPC1RAB9AHPGDGAA | |
| SCHEMBL9152364 | 0.65 | MAPT (0.46) | SMN1; SMN2GPR88POLBGAATP53 | |
| SCHEMBL9152358 | 0.65 | MAPT (0.46) | SMN1; SMN2GPR88POLBGAATP53 | |
| SCHEMBL15787498 | 0.64 | ROCK2 (0.52) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL15787501 | 0.64 | ROCK2 (0.52) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL13611896 | 0.64 | GPR88 (0.49) | SMN1; SMN2GPR88POLBLMNAALDH1A1 | |
| SCHEMBL2264435 | 0.63 | ALDH1A1 (0.61) | SMN1; SMN2NPC1RAB9AHPGDGAA | |
| SCHEMBL11266612 | 0.62 | USP2 (0.44) | SMN1; SMN2NPC1RAB9AHPGDGPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849951-A | Synthesis of carboxylic and hydroxamic acid derivatives | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-12-15 | — | — | US | disclosed |