SCHEMBL8535137

SCHEMBL8535137

Cc1ccc[c]c1Oc1ccc(N)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TEAD4 Q15561 1/20 0.47
ALDH1A1 P00352 8/20 0.46
MAPT P10636 5/20 0.46
TDP1 Q9NUW8 4/20 0.46
POLB P06746 1/20 0.46
CYP3A4 P08684 2/20 0.45
TSHR P16473 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.44
MAOA P21397 2/20 0.44
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
MITF O75030 1/20 0.41
GAA P10253 1/20 0.41
GFER P55789 1/20 0.41
NLRP1 Q9C000 1/20 0.41
NOD2 Q9HC29 1/20 0.41
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
MAPK1 P28482 2/20 0.39
HPGD P15428 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2265981 0.84 LTA4H (0.45) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL982444 0.83 LTA4H (0.42) ALDH1A1MAPTTSHRSMN1; SMN2MAOA
SCHEMBL8700822 0.82 MAOA (0.38) ALDH1A1MAPTCYP3A4SMN1; SMN2MAOA
SCHEMBL2266804 0.81 ALDH1A1 (0.38) ALDH1A1MAPTTDP1CYP3A4TSHR
SCHEMBL3348234 0.80 NCOA1 (0.47) TEAD4ALDH1A1MAPTTDP1POLB
SCHEMBL2262443 0.79 ALDH1A1 (0.44) ALDH1A1MAPTTDP1POLBCYP3A4
SCHEMBL2264013 0.72 SMN1; SMN2 (0.45) ALDH1A1MAPTPOLBCYP3A4TSHR
SCHEMBL422932 0.72 MAOA (0.43) ALDH1A1MAPTCYP3A4TSHRSMN1; SMN2
SCHEMBL8121673 0.71 LMNA (0.47) ALDH1A1TDP1CYP3A4SMN1; SMN2CYP1A2
SCHEMBL16659204 0.71 TEAD4 (0.56) TEAD4ALDH1A1MAPTTDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5780145-A CURED EPXOY AND OR IMIDE RESINS WITH FILLERS AND GLOBULAR POWDER WITH SPECIFIC PARTICLE SIZE USED AS A SEALING MATERIALS FOR SEMICONDUCTORS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-07-14 US disclosed
US-5750789-A FROM CORRESPONDING DIAMINE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-05-12 US disclosed
US-5734008-A AROMATIC ETHERDIAMINES FOR POLYIMIDE FILMS FOR PRINTED CIRCUITS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-03-31 US disclosed
US-5719225-A RESIN COMPOSITION CONTAINING FILLER COMPRISING GLOBULAR POWDERS OF DIFFERENT PARTICLE SIZES IN SPECIFIED RATIOS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1998-02-17 US disclosed