Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 10/20 | 0.38 |
| ▸ | TUBB | P07437 | 10/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 10/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 10/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 10/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 10/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 10/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 10/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 10/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 10/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 10/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 10/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 10/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 10/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 10/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432815 | 0.76 | ITGB3 (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8532447 | 0.75 | PTGS1 (0.40) | DHODHL3MBTL1CA1CA2MEN1 | |
| SCHEMBL8429187 | 0.74 | ITGB3 (0.37) | L3MBTL1CA1CA2 | |
| SCHEMBL8532340 | 0.71 | PTGS1 (0.39) | DHODHL3MBTL1CA1CA2KDM4E | |
| SCHEMBL8530525 | 0.71 | ABCB11 (0.54) | CA1CA2 | |
| SCHEMBL8430946 | 0.70 | SRD5A2 (0.39) | NR1H4CA1CA2KDM4EMEN1 | |
| SCHEMBL8537256 | 0.69 | L3MBTL1 (0.40) | DHODHL3MBTL1CA12CA9CA1 | |
| SCHEMBL8431244 | 0.69 | ITGB3 (0.37) | L3MBTL1CA1CA2 | |
| SCHEMBL8432521 | 0.69 | ABCB11 (0.41) | CA1CA2 | |
| Propionic Acid SCHEMBL8698743 | 0.69 | MAPT (0.38) | L3MBTL1CA1CA2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |