Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542267 | 0.84 | TBXAS1 (0.49) | TBXAS1LMNAMAPTTDP1NAMPT | |
| SCHEMBL8537670 | 0.82 | TBXAS1 (0.57) | TBXAS1MAPTNAMPT | |
| SCHEMBL8538995 | 0.82 | TBXAS1 (0.57) | TBXAS1MAPTNAMPT | |
| SCHEMBL8536914 | 0.81 | TBXAS1 (0.56) | TBXAS1MMP2MMP9MMP8HSD17B3 | |
| SCHEMBL4642330 | 0.81 | THRA (0.57) | TBXAS1HSD17B3HAO1 | |
| SCHEMBL5597244 | 0.80 | THRA (0.55) | TBXAS1HSD17B3HAO1 | |
| SCHEMBL7196791 | 0.79 | L3MBTL1 (0.55) | MMP2MMP9MMP8HSD17B3HAO1 | |
| SCHEMBL4642761 | 0.79 | THRA (0.53) | TBXAS1HSD17B3HAO1 | |
| SCHEMBL4640753 | 0.77 | TBXAS1 (0.52) | TBXAS1HSD17B3HAO1L3MBTL1NAMPT | |
| SCHEMBL8540514 | 0.76 | TBXAS1 (0.44) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750532-A | TETRAHYDROPYRIMIDINE-2,4-DIONE DERIVATIVES, VIRICIDES, ANTIINFLAMMATORY AGENTS, PAF INHIBITORS | SCHERING CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |