SCHEMBL8540514

SCHEMBL8540514

CSc1ccc(OCCCCCCc2ncc[nH]2)cc1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 2/20 0.44
CYP1A2 P05177 2/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2D6 P10635 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
CYP19A1 P11511 1/20 0.43
TERT O14746 1/20 0.38
HRH3 Q9Y5N1 4/20 0.34
KCNH2 Q12809 1/20 0.34
TAAR1 Q96RJ0 2/20 0.34
MAOB P27338 1/20 0.33
AOC3 Q16853 1/20 0.33
GAA P10253 1/20 0.33
NR5A1 Q13285 1/20 0.33
SLC6A4 P31645 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11759137 0.81 CYP1A2 (0.39) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL8535825 0.79 LTA4H (0.50) TBXAS1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL8538925 0.78 TBXAS1 (0.46) TBXAS1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL8535738 0.78 HRH3 (0.47) TBXAS1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL8535683 0.77 TBXAS1 (0.45) TBXAS1TERTTAAR1SLC6A4
Hydrochloric Acid SCHEMBL8540614 0.77 GAA (0.61) TBXAS1HRH3MAOBGAA
Hydrochloric Acid SCHEMBL8537563 0.77 TBXAS1 (0.47) TBXAS1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL8536355 0.76 TBXAS1 (0.57) TBXAS1
SCHEMBL9808289 0.76 KCNA3 (0.48) CYP1A2MAOBAOC3GAANR5A1
SCHEMBL8542267 0.76 TBXAS1 (0.49) TBXAS1TERTTAAR1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750532-A TETRAHYDROPYRIMIDINE-2,4-DIONE DERIVATIVES, VIRICIDES, ANTIINFLAMMATORY AGENTS, PAF INHIBITORS SCHERING CORPORATION (US) 1998-05-12 US disclosed