Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 4/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.35 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371141 | 0.91 | TGFBR1 (0.38) | TGFBR1GAAGFERAPOBEC3GFABP4 | |
| SCHEMBL8534712 | 0.89 | TGFBR1 (0.35) | TGFBR1NR1I2GAAGFERAPOBEC3G | |
| SCHEMBL8539904 | 0.87 | GHSR (0.37) | TGFBR1NR1I2GAAGFERAPOBEC3G | |
| SCHEMBL7371922 | 0.86 | VKORC1 (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8539266 | 0.85 | HDAC8 (0.37) | TGFBR1NR1I2GAAGFERAPOBEC3G | |
| SCHEMBL8534806 | 0.82 | HDAC8 (0.36) | TGFBR1GAAFABP4PDE4AMEN1 | |
| SCHEMBL7378472 | 0.80 | TGFBR1 (0.36) | TGFBR1GAAGFERAPOBEC3GFABP4 | |
| SCHEMBL7367288 | 0.79 | PTGES (0.38) | TGFBR1GAAGFERAPOBEC3GFABP4 | |
| SCHEMBL7367450 | 0.77 | HTR6 (0.38) | TGFBR1NR1I2GAAFABP4PGR | |
| SCHEMBL8539163 | 0.76 | MEN1 (0.38) | GAAGFERAPOBEC3GPDE4AGPR27 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |