Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537566 | 0.91 | MAPT (0.43) | HPGDSMN1; SMN2MAPK1MAPTNPC1 | |
| SCHEMBL8151048 | 0.79 | LMNA (0.48) | LMNAKMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL14159845 | 0.78 | LMNA (0.42) | LMNAKMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL14421361 | 0.76 | LMNA (0.46) | LMNACES2CES1DAOTSHR | |
| SCHEMBL3519272 | 0.75 | FFAR3 (0.50) | KMT2AMEN1CYP2C9ALDH1A1 | |
| SCHEMBL402908 | 0.74 | CETP (0.46) | LMNAKMT2AHPGDCES2CES1 | |
| SCHEMBL20228048 | 0.71 | SIGMAR1 (0.44) | LMNATSHRALDH1A1CYP2D6 | |
| SCHEMBL30893604 | 0.68 | LMNA (0.42) | LMNAKMT2ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL11629233 | 0.68 | LMNA (0.42) | LMNAMAPK1MAPTCES2CES1 | |
| SCHEMBL24204407 | 0.68 | OPRM1 (0.43) | KMT2AMEN1CYP2C9KCNA3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | claimed |
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |