Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535832 | 0.75 | — | — | |
| SCHEMBL6965774 | 0.68 | POLB (0.46) | CYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL8535828 | 0.66 | BACE1 (0.45) | CYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL6966115 | 0.64 | POLB (0.43) | POLB | |
| SCHEMBL6954167 | 0.64 | GABRA1 (0.43) | CYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL3620532 | 0.63 | EDNRA (0.43) | — | |
| SCHEMBL7391020 | 0.63 | GABRA1 (0.33) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9156184 | 0.62 | CA2 (0.36) | — | |
| SCHEMBL4610712 | 0.61 | — | — | |
| SCHEMBL6955616 | 0.61 | POLB (0.41) | CYP2D6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | claimed |