Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FADS1 | O60427 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1342200 | 0.93 | KEAP1 (0.56) | KEAP1HSD11B1L3MBTL1FADS1HDAC2 | |
| SCHEMBL5278682 | 0.92 | KEAP1 (0.54) | KEAP1HSD11B1FADS1HDAC2HDAC3 | |
| SCHEMBL4674613 | 0.90 | KEAP1 (0.53) | KEAP1HSD11B1FADS1HDAC2HDAC3 | |
| SCHEMBL4674606 | 0.89 | KEAP1 (0.51) | KEAP1HSD11B1L3MBTL1FADS1HDAC2 | |
| SCHEMBL11749982 | 0.86 | HTR1F (0.52) | KEAP1HSD11B1L3MBTL1HDAC2HDAC3 | |
| SCHEMBL8105872 | 0.84 | KEAP1 (0.46) | KEAP1HSD11B1HDAC2HDAC3HDAC1 | |
| SCHEMBL31231867 | 0.80 | PIN1 (0.56) | HSD11B1L3MBTL1CES2CES1ALDH1A1 | |
| SCHEMBL1342037 | 0.79 | HDAC3 (0.46) | KEAP1HSD11B1L3MBTL1HDAC2HDAC3 | |
| SCHEMBL2471282 | 0.79 | RECQL (0.56) | FADS1ALDH1A1MEN1KMT2A | |
| SCHEMBL30590434 | 0.79 | RECQL (0.56) | FADS1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679646-B1 | Sulfonyl ureas as herbicidal compounds | AMERICAN CYANAMID CO (US) | 1998-07-29 | — | — | EP | claimed |
| EP-0679646-A1 | Sulfonyl ureas as herbicidal compounds | AMERICAN CYANAMID COMPANY (US) | 1995-11-02 | — | — | EP | claimed |
| JP-7304754-A | — | — | None | — | — | JP | disclosed |
| CN-1067382-C | 1-{[2-(cyclopropylcarbonyl)-4-fluorophenyl] sulfamoyl}-3-(4,6-Dimethoxy-2-pyrimidinyl)urea and itsd herbicidal | AMERICAN CYANAMID CO (US) | 2001-06-20 | — | — | CN | disclosed |
| EP-0682007-B1 | Method for the preparation of 4-halo-2'-nitrobutyrophenone | AMERICAN CYANAMID CO (US) | 1998-10-07 | — | — | EP | disclosed |
| EP-0679646-B1 | Sulfonyl ureas as herbicidal compounds | AMERICAN CYANAMID CO (US) | 1998-07-29 | — | — | EP | disclosed |
| US-5599996-A | CHEMICAL INTERMEDIATES FOR HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| US-5599996-A | CHEMICAL INTERMEDIATES FOR HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| US-5492884-A | PREEMERGENCE, POSTEMERGENCE | AMERICAN CYANAMID COMPANY (US) | 1996-02-20 | — | — | US | disclosed |
| CN-1112923-A | 1-{[2-(cyclopropylcarbonyl)-4-fluorophenyl] sulfamoyl}-3-(4,6-Dimethoxy-2-pyrimidinyl)urea and itsd herbicidal | AMERICAN CYANAMID CO (US) | 1995-12-06 | — | — | CN | disclosed |
| JP-H07304754-A | 1-((2-(CYCLOPROPYLCARBONYL)-4-FLUOROPHENYL)SULFAMOYL)-3-(4,6-DIMETHOXY2-PYRIMIDINYL) UREA AND ITS HERBICIDAL USE | AMERICAN CYANAMID CO | 1995-11-21 | — | — | JP | disclosed |
| EP-0682007-A1 | Method for the preparation of 4-halo-2'-nitrobutyrophenone | AMERICAN CYANAMID COMPANY (US) | 1995-11-15 | — | — | EP | disclosed |
| EP-0679646-A1 | Sulfonyl ureas as herbicidal compounds | AMERICAN CYANAMID COMPANY (US) | 1995-11-02 | — | — | EP | disclosed |