Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.40 |
| ▸ | ITGAV | P06756 | 11/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534198 | 0.78 | LMNA (0.40) | ITGB3ITGAVMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8531545 | 0.77 | PARP1 (0.34) | ITGB3ITGAVITGA2BMEN1KMT2A | |
| SCHEMBL8501217 | 0.77 | ITGB3 (0.45) | ITGB3ITGAVITGA2BMEN1KMT2A | |
| SCHEMBL7864761 | 0.75 | ITGB3 (0.43) | ITGB3ITGAVITGA2BMEN1KMT2A | |
| SCHEMBL8534056 | 0.75 | CASR (0.39) | ITGB3ITGAV | |
| SCHEMBL8501220 | 0.74 | ITGB3 (0.42) | ITGB3ITGAVITGA2BMEN1KMT2A | |
| SCHEMBL7863285 | 0.74 | ITGB3 (0.48) | ITGB3ITGAVITGA2BPOLBMAPT | |
| SCHEMBL8534303 | 0.73 | ITGB3 (0.41) | ITGB3ITGAVITGA2BPOLBSMN1; SMN2 | |
| SCHEMBL8532970 | 0.73 | CTSA (0.43) | ITGB3ITGAV | |
| SCHEMBL7863196 | 0.71 | MAPT (0.50) | ITGB3ITGA2BSIRT2SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |