Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 13/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | CASP7 | P55210 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | TOP2A | P11388 | 2/20 | 0.53 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539401 | 0.91 | NISCH (0.66) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL8537356 | 0.90 | NISCH (0.59) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL6751823 | 0.86 | TOP2A (0.63) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL105024 | 0.79 | NISCH (1.00) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL28772851 | 0.77 | NISCH (0.96) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| Bromide SCHEMBL29039569 | 0.77 | NISCH (0.96) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| Ammonia Solution, Strong SCHEMBL7104964 | 0.77 | NISCH (0.96) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL6751839 | 0.76 | TOP2A (0.66) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL8141372 | 0.76 | NISCH (1.00) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| Furaline SCHEMBL11783413 | 0.76 | ALDH1A1 (0.84) | NISCHALDH1A1CYP1A2HPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723288-A | Method of fluorescent detection of nucleic acids and cytoskeleton elements using bis-dicationic aryl furans, and kits useful therefor | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1998-03-03 | — | — | US | disclosed |