Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536831 | 0.85 | KCNK3 (0.46) | ALDH1A1PLAUMEN1KMT2ARXFP1 | |
| SCHEMBL8539472 | 0.82 | PARP1 (0.47) | ALDH1A1PLAURAB9ANPC1MEN1 | |
| SCHEMBL8537945 | 0.80 | PTGS1 (0.46) | RAB9AMEN1KMT2ARXFP1KCNK3 | |
| SCHEMBL8542403 | 0.80 | KCNK3 (0.41) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL8542656 | 0.76 | KCNK3 (0.50) | ALDH1A1PLAURAB9ANPC1MEN1 | |
| SCHEMBL9304048 | 0.74 | SIRT2 (0.55) | PLAUMEN1KMT2ARXFP1KCNK3 | |
| SCHEMBL8540350 | 0.73 | ITGB3 (0.50) | ALDH1A1PLAURAB9ANPC1MEN1 | |
| SCHEMBL7975430 | 0.73 | ALDH1A1 (0.72) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9303041 | 0.73 | PLAU (0.61) | PLAUMEN1KMT2ARXFP1KCNK3 | |
| SCHEMBL895690 | 0.72 | MEN1 (0.63) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |