Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536796 | 0.85 | ALDH1A1 (0.46) | KCNK3KCNK9KMT2AMEN1RXFP1 | |
| SCHEMBL8537945 | 0.82 | PTGS1 (0.46) | KCNK3KCNK9KMT2AMEN1RXFP1 | |
| SCHEMBL8542403 | 0.82 | KCNK3 (0.41) | KCNK3KCNK9KMT2AMEN1KCNH2 | |
| SCHEMBL8539472 | 0.80 | PARP1 (0.47) | KCNK3KCNK9KMT2AMEN1RXFP1 | |
| SCHEMBL8542656 | 0.79 | KCNK3 (0.50) | KCNK3KCNK9KMT2AMEN1KCNH2 | |
| SCHEMBL9304048 | 0.77 | SIRT2 (0.55) | KCNK3KCNK9KMT2AMEN1RXFP1 | |
| SCHEMBL9303041 | 0.76 | PLAU (0.61) | KCNK3KCNK9KMT2AMEN1KCNH2 | |
| SCHEMBL9303308 | 0.74 | PTGES (0.56) | KCNK3KCNK9KMT2AMEN1RXFP1 | |
| SCHEMBL6930688 | 0.74 | KMT2A (0.62) | KMT2AMEN1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8542529 | 0.74 | ITGB3 (0.50) | KCNK3KCNK9SIRT2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |