Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
| ▸ | ITGAV | P06756 | 2/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537007 | 0.95 | PTGIR (0.39) | PTGIRADRA2A | |
| SCHEMBL8538800 | 0.86 | ITGB3 (0.39) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8539100 | 0.80 | ADRA2A (0.39) | PTGIRADRA2AITGB3ITGAV | |
| SCHEMBL8540200 | 0.69 | ITGB3 (0.41) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8536842 | 0.69 | PTGIR (0.41) | PTGIRADRA2AITGB3ITGAVITGA2B | |
| SCHEMBL8542609 | 0.68 | ITGB3 (0.41) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8542532 | 0.65 | TLR4 (0.36) | — | |
| SCHEMBL8431443 | 0.64 | ITGB3 (0.38) | PTGIRITGB3ITGAVITGA2BITGB1 | |
| SCHEMBL8542414 | 0.63 | PTGIR (0.39) | PTGIRADRA2AITGB3ITGAVITGA2B | |
| SCHEMBL8537009 | 0.62 | PTGIR (0.47) | PTGIRADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |