Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.39 |
| ▸ | ITGAV | P06756 | 18/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 8/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 8/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539100 | 0.94 | ADRA2A (0.39) | ITGB3ITGAV | |
| SCHEMBL8536838 | 0.86 | PTGIR (0.34) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8540200 | 0.83 | ITGB3 (0.41) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8537007 | 0.80 | PTGIR (0.39) | — | |
| SCHEMBL8542532 | 0.79 | TLR4 (0.36) | — | |
| SCHEMBL8538619 | 0.66 | ITGB3 (0.52) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8541934 | 0.65 | ITGB3 (0.46) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8538377 | 0.65 | HTR1D (0.42) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8544830 | 0.64 | ITGB3 (0.60) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL11283477 | 0.64 | ADRA2A (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |