Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 7/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538800 | 0.94 | ITGB3 (0.39) | ITGB3ITGAV | |
| SCHEMBL8537007 | 0.85 | PTGIR (0.39) | ADRA2AADRA1AHTR7ADRA2BADRA2C | |
| SCHEMBL8542532 | 0.81 | TLR4 (0.36) | — | |
| SCHEMBL8536838 | 0.80 | PTGIR (0.34) | ADRA2AITGB3ITGAVPTGIR | |
| SCHEMBL8540200 | 0.77 | ITGB3 (0.41) | ITGB3ITGAV | |
| SCHEMBL8538377 | 0.70 | HTR1D (0.42) | ADRA2AADRA1AHTR7ADRA2BADRA2C | |
| SCHEMBL11162946 | 0.70 | NISCH (0.59) | ADRA2AADRA1AHTR7ADRA2BADRA2C | |
| SCHEMBL8538079 | 0.65 | ITGB3 (0.48) | ADRA2AADRA2BADRA2CITGB3ITGAV | |
| SCHEMBL6788672 | 0.64 | ADRA2A (0.59) | ADRA2AADRA1AHTR7ADRA2BADRA2C | |
| SCHEMBL17887763 | 0.64 | HTR1D (0.59) | ADRA2AADRA1AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |