Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 12/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 10/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 10/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536838 | 0.95 | PTGIR (0.34) | PTGIRADRA2A | |
| SCHEMBL8539100 | 0.85 | ADRA2A (0.39) | PTGIRADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL8537009 | 0.68 | PTGIR (0.47) | PTGIRADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL8542414 | 0.67 | PTGIR (0.39) | PTGIRADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL8542532 | 0.67 | TLR4 (0.36) | — | |
| SCHEMBL8540200 | 0.63 | ITGB3 (0.41) | — | |
| SCHEMBL8542609 | 0.63 | ITGB3 (0.41) | — | |
| SCHEMBL8536842 | 0.62 | PTGIR (0.41) | PTGIRADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL7373771 | 0.61 | ITGB3 (0.47) | PTGIRADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL7844560 | 0.60 | ITGB3 (0.47) | PTGIRADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |