Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540333 | 0.89 | TBXAS1 (0.50) | TBXAS1PPARGPPARAGAAALDH1A1 | |
| SCHEMBL8536914 | 0.82 | TBXAS1 (0.56) | TBXAS1NAMPTPTGS2GSR | |
| SCHEMBL8538925 | 0.76 | TBXAS1 (0.46) | TBXAS1CA2PTGS2 | |
| SCHEMBL8538471 | 0.75 | SMN1; SMN2 (0.50) | TBXAS1GAAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8536865 | 0.73 | TBXAS1 (0.46) | TBXAS1NAMPT | |
| SCHEMBL9266643 | 0.72 | TBXAS1 (0.46) | TBXAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8542267 | 0.71 | TBXAS1 (0.49) | TBXAS1GAAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8537670 | 0.69 | TBXAS1 (0.57) | TBXAS1GAAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8538995 | 0.69 | TBXAS1 (0.57) | TBXAS1GAAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1093234 | 0.69 | TBXAS1 (0.68) | TBXAS1ALDH1A1SMN1; SMN2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750532-A | TETRAHYDROPYRIMIDINE-2,4-DIONE DERIVATIVES, VIRICIDES, ANTIINFLAMMATORY AGENTS, PAF INHIBITORS | SCHERING CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |