Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | GSR | P00390 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538489 | 0.89 | TBXAS1 (0.46) | TBXAS1NAMPTPTGS2GSRGAA | |
| SCHEMBL8536914 | 0.86 | TBXAS1 (0.56) | TBXAS1NAMPTPTGS2GSR | |
| SCHEMBL8542267 | 0.81 | TBXAS1 (0.49) | TBXAS1NAMPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8538471 | 0.81 | SMN1; SMN2 (0.50) | TBXAS1NAMPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8538925 | 0.77 | TBXAS1 (0.46) | TBXAS1PTGS2 | |
| SCHEMBL8536865 | 0.76 | TBXAS1 (0.46) | TBXAS1NAMPTTAAR1 | |
| SCHEMBL9263151 | 0.71 | TBXAS1 (0.49) | TBXAS1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL9263145 | 0.71 | TBXAS1 (0.49) | TBXAS1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL29429430 | 0.71 | PTGS2 (0.47) | PTGS2GSR | |
| SCHEMBL9373261 | 0.70 | TBXAS1 (0.73) | TBXAS1NAMPTGAASMN1; SMN2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750532-A | TETRAHYDROPYRIMIDINE-2,4-DIONE DERIVATIVES, VIRICIDES, ANTIINFLAMMATORY AGENTS, PAF INHIBITORS | SCHERING CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |