Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 2/20 | 0.49 |
| ▸ | JAK1 | P23458 | 3/20 | 0.41 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534849 | 0.73 | GPR132 (0.38) | GPR132 | |
| SCHEMBL7369214 | 0.69 | TP53 (0.40) | TYK2GPR132KMT2A | |
| SCHEMBL8535930 | 0.67 | VCP (0.39) | GPR132GPR119 | |
| SCHEMBL2240663 | 0.66 | TYK2 (1.00) | TYK2JAK1JAK2JAK3 | |
| SCHEMBL7371304 | 0.64 | PRKDC (0.39) | TYK2GPR132ADAMTS4GPR119 | |
| SCHEMBL13731309 | 0.64 | TYK2 (0.57) | TYK2JAK1GSK3BJAK2JAK3 | |
| SCHEMBL13535430 | 0.63 | JAK1 (0.71) | TYK2JAK1JAK2JAK3 | |
| SCHEMBL7457650 | 0.62 | GPR132 (0.40) | GPR132KMT2A | |
| SCHEMBL28048524 | 0.62 | MAPK1 (0.64) | GPR132MEN1KMT2ARAB9A | |
| SCHEMBL8540378 | 0.62 | ACHE (0.48) | ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |