Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537608 | 0.91 | L3MBTL1 (0.54) | POLBL3MBTL1KMT2AALDH1A1GAA | |
| SCHEMBL8482735 | 0.84 | TEAD3 (0.43) | POLBL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL8482314 | 0.84 | ALDH1A1 (0.38) | POLBL3MBTL1MEN1KMT2AUSP2 | |
| SCHEMBL8537598 | 0.78 | KCNH2 (0.44) | POLBL3MBTL1MAPTUSP2ALDH1A1 | |
| SCHEMBL8482611 | 0.78 | L3MBTL1 (0.41) | POLBL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL8560245 | 0.77 | ALDH1A1 (0.43) | POLBL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL8481805 | 0.75 | ALDH1A1 (0.48) | POLBL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL5551312 | 0.73 | KDM4E (0.43) | POLBL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL5557277 | 0.72 | ALDH1A1 (0.46) | POLBL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL8302334 | 0.72 | PIK3CD (0.38) | L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485045-B1 | Mono-N-substituted 1,4,7,10-Tetraazacyclododecan-derivatives, process for their preparation and pharmaceutical agent containing them | SCHERING AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| US-5277895-A | Nuclear magnetic resonance | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-01-11 | — | — | US | disclosed |
| EP-0485045-A2 | Mono-N-substituted 1,4,7,10-Tetraazacyclododecan-derivatives, process for their preparation and pharmaceutical agent containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-05-13 | — | — | EP | disclosed |