Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537604 | 0.91 | POLB (0.41) | L3MBTL1POLBALDH1A1HTTGAA | |
| SCHEMBL8482735 | 0.90 | TEAD3 (0.43) | L3MBTL1POLBALDH1A1TSHRGAA | |
| SCHEMBL8482611 | 0.84 | L3MBTL1 (0.41) | L3MBTL1POLBKDM4EALDH1A1TSHR | |
| SCHEMBL8482314 | 0.81 | ALDH1A1 (0.38) | L3MBTL1POLBKDM4EALDH1A1KMT2A | |
| SCHEMBL8537606 | 0.80 | L3MBTL1 (0.56) | L3MBTL1POLBKDM4EALDH1A1LMNA | |
| SCHEMBL5557209 | 0.76 | BACE1 (0.39) | L3MBTL1POLBKDM4EALDH1A1KMT2A | |
| SCHEMBL8560245 | 0.74 | ALDH1A1 (0.43) | L3MBTL1POLBKDM4EALDH1A1HTT | |
| SCHEMBL5555228 | 0.73 | ALDH1A1 (0.43) | L3MBTL1POLBKDM4EALDH1A1TSHR | |
| SCHEMBL8481805 | 0.73 | ALDH1A1 (0.48) | L3MBTL1POLBKDM4EALDH1A1LMNA | |
| SCHEMBL9315964 | 0.72 | ITGB3 (0.47) | L3MBTL1POLBKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485045-B1 | Mono-N-substituted 1,4,7,10-Tetraazacyclododecan-derivatives, process for their preparation and pharmaceutical agent containing them | SCHERING AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| US-5277895-A | Nuclear magnetic resonance | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-01-11 | — | — | US | disclosed |
| EP-0485045-A2 | Mono-N-substituted 1,4,7,10-Tetraazacyclododecan-derivatives, process for their preparation and pharmaceutical agent containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-05-13 | — | — | EP | disclosed |